ORIZURU THERAPEUTICS INC.: Regenerative Medicine and Drug Discovery using iPS technology

Top 5 Biotech Startups in Japan – 2022

Currently, biotechnology startups place a greater emphasis on automation and computer-aided drug development. The most recent industry trends include the incorporation of AI, the development of personalized medicine, an increase in digital diagnosis, and a greater emphasis on immune cell functions.

The global Biotechnology services market was estimated at US$ 129.15 billion in 2021 and has grown at a compound annual growth rate (CAGR) of 15.6% to US$ 149.32. These trends have contributed to the potential for a sizable market for companies to invest further in the biotechnology startup sector.

This issue of Startup City features the ‘Top 5 Biotech startups in Japan - 2022’ which highlights some of the most important developments in the Japanese biotechnology space, as well as how biotechnology startups are operating in the current business environment and how they improve productivity and profitability.

The edition also includes a list of the ‘Top 10 Biotech Startups in APAC,’ highlighting the trends and developments in biotechnology startups throughout the Asia-Pacific region.

Furthermore, it includes the ‘Top 5 Biotech Startups in Singapore - 2022’ and ‘Top 5 Biotech Startups in South Korea - 2022’ which go into greater detail about the characteristics, trends, and developments of biotechnology startups in the respective regions.

It includes companies such as Orizuru Therapeutics, which was founded in 2021 as collaboration between Kyoto University and Takeda Pharmaceutical Company to research and commercialize iPS cell-based medicines. It is primarily concerned with cell regeneration therapy, regenerative medicine products derived from cell transplantation, and medication development.

The magazine also highlights the opinions of Michael Krel, Partner, Industrial Biotech Strategy, Sofinnova Partners, and Dr. Dan Liu, Partner in Venture and Growth Capital, CDH Investments. They respectively discuss the biotechnology industry’s evolution, challenges, and future, as well as how the industry is shaping up in China’s currently volatile business environment.

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    Top Biotech Startups in Japan

    Orizuru Therapeutics was created in 2021 as a collaboration between Kyoto University and Takeda Pharmaceutical Company, to research and develop products on iPS cell technology. It mainly focuses on cell regeneration therapy, regenerative medicine products by cell transplantation, and drug discovery. ... read full profile
    VC Cell Therapy, founded two years ago, is focused on offering practical application of regenerative therapy to treat retinal degeneration. The company leverages iPS cell-derived pigment epithelial (iPS-RPE) to effectively treat age-related macular degeneration, retinitis pigmentosa, and other retinal orphan diseases. ... read full profile
    ARTham Therapeutics
    ARTham Therapeutics Inc., is a clinical stage biopharmaceutical company that will deliver ‘medicines that matter’ for patients. Their goal is to create innovative medicines that are disease modifying and satisfy significant unmet medical need. To deliver on cost and time efficiency, ARTham will run a virtual R&D operating model that seeks innovation through the best academic and business partners
    Cuorips
    Cuorips develops unprecedented effective medical care by utilizing reliable and safe technology. The company’s first challenge is to promote research and development on manufacturing methods for iPS cell-derived cardiomyocyte sheets, establish more efficient production technology, and aim to obtain approval for manufacturing and marketing as a regenerative medicine product
    GRA&GREEN
    GRA&GREEN offers accelerated breeding programs to create nextgeneration food and agriculture by using its genome editing system. Genome editing is one of the solutions for rapid breed development. It is an epochmaking technique that can cut the target site of a gene. As a result, changes may occur in the cut site, which is used in new varieties